Stem-loop sequence hsa-mir-523

Accession

MI0003153

Symbol

HGNC:MIR523

Description

Homo sapiens miR-523 stem-loop

Gene family

MIPF0000020; mir-515

Stem-loop

     ugcu           g          u    guug  u 
ucuca    gugacccucua agggaagcgc uucu    uc g
|||||    ||||||||||| |||||||||| ||||    || a
agagu    cauugggagau ucccuucgcg aaga    ag a
     uucc           a          c    --aa  a 

Deep sequencing

9 reads, 3 experiments

Genome context

• Coordinates (GRCh37.p5): chr19: 54201639-54201725 [+]
• Overlapping transcripts:

  intergenic

Clustered miRNAs

< 10kb from hsa-mir-523

• hsa-mir-1283-1: chr19: 54191735-54191821 [+]
• hsa-mir-520a: chr19: 54194135-54194219 [+]
• hsa-mir-526b: chr19: 54197647-54197729 [+]
• hsa-mir-519b: chr19: 54198467-54198547 [+]
• hsa-mir-525: chr19: 54200787-54200871 [+]
• hsa-mir-523: chr19: 54201639-54201725 [+]
• hsa-mir-518f: chr19: 54203269-54203355 [+]
• hsa-mir-520b: chr19: 54204481-54204541 [+]
• hsa-mir-518b: chr19: 54205991-54206073 [+]
• hsa-mir-526a-1: chr19: 54209506-54209590 [+]
• hsa-mir-520c: chr19: 54210707-54210793 [+]

Database links

• EMBL: AY785942;AY785942
• EMBL: AY882326;AY882326
• ENTREZGENE: 574471;MIR523
• HGNC: 32103;MIR523

Mature sequence hsa-miR-523-5p

• Accession: MIMAT0005449
• Previous IDs: hsa-miR-523*
• Sequence: 16 - cucuagagggaagcgcuuucug - 37
• Deep sequencing: 8 reads, 2 experiments
• Evidence: experimental; array-cloned [1], cloned [2]
• Predicted targets:
  • DIANA-MICROT:hsa-miR-523-5p
  • MICRORNA.ORG:hsa-miR-523-5p
  • MIRDB:hsa-miR-523-5p
  • RNA22-HSA:hsa-miR-523-5p
  • TARGETMINER:hsa-miR-523-5p

Mature sequence hsa-miR-523-3p

• Accession: MIMAT0002840
• Previous IDs: hsa-miR-523
• Sequence: 53 - gaacgcgcuucccuauagagggu - 75
• Deep sequencing: 1 reads, 1 experiments
• Evidence: experimental; array-cloned [1], cloned [2]
• Predicted targets:
  • DIANA-MICROT:hsa-miR-523-3p
  • MICRORNA.ORG:hsa-miR-523-3p
  • MIRDB:hsa-miR-523-3p
  • RNA22-HSA:hsa-miR-523-3p
  • TARGETMINER:hsa-miR-523-3p
  • TARGETSCAN-VERT:hsa-miR-523

References

1. PMID:15965474 "Identification of hundreds of conserved and nonconserved human microRNAs" Bentwich I, Avniel A, Karov Y, Aharonov R, Gilad S, Barad O, Barzilai A, Einat P, Einav U, Meiri E, Sharon E, Spector Y, Bentwich Z Nat Genet. 37:766-770(2005).
2. PMID:17604727 "A mammalian microRNA expression atlas based on small RNA library sequencing" Landgraf P, Rusu M, Sheridan R, Sewer A, Iovino N, Aravin A, Pfeffer S, Rice A, Kamphorst AO, Landthaler M, Lin C, Socci ND, Hermida L, Fulci V, Chiaretti S, Foa R, Schliwka J, Fuchs U, Novosel A, Muller RU, Schermer B, Bissels U, Inman J, Phan Q, Chien M Cell. 129:1401-1414(2007).