Stem-loop sequence hsa-mir-497

Accession

MI0003138

Symbol

HGNC:MIR497

Description

Homo sapiens miR-497 stem-loop

Gene family

MIPF0000231; mir-497

Stem-loop

  a cc    -   g         - -----    g    c         u  --   ac 
cc c  cggu ccu cucccgccc c     agca caca ugugguuug ac  ggc  u
|| |  |||| ||| ||||||||| |     |||| |||| ||||||||| ||  |||   
gg g  gcca gga ggggguggg g     uugu gugu acaccaaac ug  ccg  g
  a cc    c   -         a cgaga    g    c         c  ca   gu 

Deep sequencing

930 reads, 27 experiments

Genome context

• Coordinates (GRCh37.p5): chr17: 6921230-6921341 [-]
• Overlapping transcripts:

  sense

  OTTHUMT00000256411 ; AC027763.1-001; intron 1

  OTTHUMT00000439494 ; AC027763.2-003; intron 1

  OTTHUMT00000439495 ; AC027763.2-004; intron 1

  OTTHUMT00000439619 ; AC027763.2-012; exon 1

  OTTHUMT00000439494 ; AC027763.2-003; intron 1

  OTTHUMT00000439495 ; AC027763.2-004; intron 1

  OTTHUMT00000439619 ; AC027763.2-012; exon 1

  ENST00000443997 ; MIR497HG-001; intron 1

  ENST00000572547 ; MIR497HG-003; intron 1

  ENST00000443997 ; MIR497HG-004; intron 1

  ENST00000572453 ; MIR497HG-012; exon 1

  ENST00000572547 ; MIR497HG-003; intron 1

  ENST00000443997 ; MIR497HG-004; intron 1

  ENST00000572453 ; MIR497HG-012; exon 1

Clustered miRNAs

< 10kb from hsa-mir-497

• hsa-mir-497: chr17: 6921230-6921341 [-]
• hsa-mir-195: chr17: 6920934-6921020 [-]

Database links

• EMBL: AY785913;AY785913
• ENTREZGENE: 574456;MIR497
• HGNC: 32088;MIR497

Mature sequence hsa-miR-497-5p

• Accession: MIMAT0002820
• Previous IDs: hsa-miR-497
• Sequence: 24 - cagcagcacacugugguuugu - 44
• Deep sequencing: 927 reads, 27 experiments
• Evidence: experimental; array-cloned [1], cloned [2]
• Predicted targets:
  • DIANA-MICROT:hsa-miR-497-5p
  • MICRORNA.ORG:hsa-miR-497-5p
  • MIRDB:hsa-miR-497-5p
  • RNA22-HSA:hsa-miR-497-5p
  • TARGETMINER:hsa-miR-497-5p
  • TARGETSCAN-VERT:hsa-miR-497

Mature sequence hsa-miR-497-3p

• Accession: MIMAT0004768
• Previous IDs: hsa-miR-497*
• Sequence: 64 - caaaccacacugugguguuaga - 85
• Deep sequencing: 3 reads, 2 experiments
• Evidence: experimental; cloned [2]
• Predicted targets:
  • DIANA-MICROT:hsa-miR-497-3p
  • MICRORNA.ORG:hsa-miR-497-3p
  • MIRDB:hsa-miR-497-3p
  • RNA22-HSA:hsa-miR-497-3p
  • TARGETMINER:hsa-miR-497-3p

References

1. PMID:15965474 "Identification of hundreds of conserved and nonconserved human microRNAs" Bentwich I, Avniel A, Karov Y, Aharonov R, Gilad S, Barad O, Barzilai A, Einat P, Einav U, Meiri E, Sharon E, Spector Y, Bentwich Z Nat Genet. 37:766-770(2005).
2. PMID:17604727 "A mammalian microRNA expression atlas based on small RNA library sequencing" Landgraf P, Rusu M, Sheridan R, Sewer A, Iovino N, Aravin A, Pfeffer S, Rice A, Kamphorst AO, Landthaler M, Lin C, Socci ND, Hermida L, Fulci V, Chiaretti S, Foa R, Schliwka J, Fuchs U, Novosel A, Muller RU, Schermer B, Bissels U, Inman J, Phan Q, Chien M Cell. 129:1401-1414(2007).