Stem-loop sequence hsa-mir-493

AccessionMI0003132
Symbol HGNC:MIR493
DescriptionHomo sapiens miR-493 stem-loop
Gene family MIPF0000230; mir-493
Stem-loop
        cuc        u                    cauuc  u 
5' cuggc   cagggcuu guacaugguaggcuuucauu     gu u
   |||||   |||||||| ||||||||||||||||||||     ||  
3' gaccg   gucccgga cgugugucaucuggaagugg     ca g
        --u        c                    -cuua  c 
Get sequence
Deep sequencing
1823 reads, 529 reads per million, 41 experiments
Confidence Annotation confidence: high
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Comments

The mature miRNA sequences were named miR-493-5p and miR-493-3p in [1,2] and here. Landgraf et al. showed that the 3' product is the predominant one [3]. The mature sequence shown here represents the most commonly cloned form from large-scale cloning studies [3].

Genome context
Coordinates (GRCh38) Overlapping transcripts
chr14: 100869060-100869148 [+]
sense
OTTHUMT00000414309 ; WDR25-007; intron 1
OTTHUMT00000414313 ; WDR25-008; intron 1
OTTHUMT00000414315 ; WDR25-005; intron 1
OTTHUMT00000414316 ; WDR25-006; intron 1
OTTHUMT00000414310 ; WDR25-002; intron 2
OTTHUMT00000414311 ; WDR25-001; intron 2
OTTHUMT00000414312 ; WDR25-004; intron 2
OTTHUMT00000414314 ; WDR25-003; intron 2
ENST00000555775 ; WDR25-007; intron 1
ENST00000554492 ; WDR25-008; intron 1
ENST00000557710 ; WDR25-005; intron 1
ENST00000542471 ; WDR25-006; intron 1
ENST00000554998 ; WDR25-002; intron 2
ENST00000402312 ; WDR25-001; intron 2
ENST00000335290 ; WDR25-004; intron 2
ENST00000554175 ; WDR25-003; intron 2
Clustered miRNAs
< 10kb from hsa-mir-493
hsa-mir-493chr14: 100869060-100869148 [+]
hsa-mir-337chr14: 100874493-100874585 [+]
hsa-mir-665chr14: 100875033-100875104 [+]
Database links

Mature sequence hsa-miR-493-5p

Accession MIMAT0002813
Previous IDshsa-miR-493;hsa-miR-493-5p;hsa-miR-493*
Sequence

16 - 

uuguacaugguaggcuuucauu

 - 37

Get sequence
Deep sequencing724 reads, 30 experiments
Evidence experimental; array-cloned [1], cloned [2-3]
Predicted targets

Mature sequence hsa-miR-493-3p

Accession MIMAT0003161
Previous IDshsa-miR-493-3p;hsa-miR-493
Sequence

57 - 

ugaaggucuacugugugccagg

 - 78

Get sequence
Deep sequencing178 reads, 21 experiments
Evidence experimental; cloned [2-3]
Predicted targets

References

1
PMID:15965474 "Identification of hundreds of conserved and nonconserved human microRNAs" Bentwich I, Avniel A, Karov Y, Aharonov R, Gilad S, Barad O, Barzilai A, Einat P, Einav U, Meiri E, Sharon E, Spector Y, Bentwich Z Nat Genet. 37:766-770(2005).
2
PMID:16274478 "Identification of clustered microRNAs using an ab initio prediction method" Sewer A, Paul N, Landgraf P, Aravin A, Pfeffer S, Brownstein MJ, Tuschl T, van Nimwegen E, Zavolan M BMC Bioinformatics. 6:267(2005).
3
PMID:17604727 "A mammalian microRNA expression atlas based on small RNA library sequencing" Landgraf P, Rusu M, Sheridan R, Sewer A, Iovino N, Aravin A, Pfeffer S, Rice A, Kamphorst AO, Landthaler M, Lin C, Socci ND, Hermida L, Fulci V, Chiaretti S, Foa R, Schliwka J, Fuchs U, Novosel A, Muller RU, Schermer B, Bissels U, Inman J, Phan Q, Chien M Cell. 129:1401-1414(2007).