Stem-loop sequence mmu-mir-467a-1

Accession

MI0002402

Previous IDs

mmu-mir-467;mmu-mir-467a

Symbol

MGI:Mirn467a

Description

Mus musculus miR-467a-1 stem-loop

Gene family

MIPF0000316; mir-467

Stem-loop

c      c   a   cc  c             ua 
 ugugug gua gug  ug auguauaugcgug  u
 |||||| ||| |||  || |||||||||||||  a
 acacac cau cac  ac uacauauacguau  u
u      a   c   ac  a             uu 

Deep sequencing

19966 reads, 85 experiments

Comments

The sequence of miR-467 is of low complexity. The sequence maps exactly to several genomic positions, and many more with 1 or 2 substitutions. Confidence in this miRNA might therefore be reduced.

Genome context

• Coordinates (GRCm38): chr2: 10476346-10476418 [+]
• Overlapping transcripts:

  sense

  OTTMUST00000026263 ; Sfmbt2-001; intron 10

  ENSMUST00000041105 ; Sfmbt2-001; intron 10

  ENSMUST00000116594 ; Sfmbt2-201; intron 11

Clustered miRNAs

< 10kb from mmu-mir-467a-1

• mmu-mir-466m: chr2: 10466663-10466746 [+]
• mmu-mir-466f-1: chr2: 10466944-10467037 [+]
• mmu-mir-669f: chr2: 10467229-10467349 [+]
• mmu-mir-669e: chr2: 10467495-10467613 [+]
• mmu-mir-669b: chr2: 10467790-10467886 [+]
• mmu-mir-669d: chr2: 10468343-10468463 [+]
• mmu-mir-466f-2: chr2: 10468675-10468768 [+]
• mmu-mir-669l: chr2: 10468971-10469068 [+]
• mmu-mir-669d-2: chr2: 10471644-10471729 [+]
• mmu-mir-466f-3: chr2: 10471953-10472046 [+]
• mmu-mir-297a-2: chr2: 10472254-10472343 [+]
• mmu-mir-466o: chr2: 10472540-10472623 [+]
• mmu-mir-467c: chr2: 10473931-10474027 [+]
• mmu-mir-466b-1: chr2: 10474219-10474300 [+]
• mmu-mir-669a-3: chr2: 10474433-10474541 [+]
• mmu-mir-669k: chr2: 10475300-10475426 [+]
• mmu-mir-467a-1: chr2: 10476346-10476418 [+]
• mmu-mir-466b-8: chr2: 10476628-10476713 [+]
• mmu-mir-669a-1: chr2: 10476853-10476949 [+]
• mmu-mir-669g: chr2: 10477150-10477272 [+]
• mmu-mir-669j: chr2: 10477910-10478030 [+]
• mmu-mir-467a-2: chr2: 10478798-10478880 [+]
• mmu-mir-466e: chr2: 10479088-10479171 [+]
• mmu-mir-669a-4: chr2: 10479315-10479401 [+]
• mmu-mir-467b: chr2: 10481248-10481320 [+]
• mmu-mir-466c-1: chr2: 10481534-10481617 [+]
• mmu-mir-669a-5: chr2: 10481761-10481847 [+]
• mmu-mir-467a-3: chr2: 10483678-10483760 [+]
• mmu-mir-466c-2: chr2: 10483966-10484055 [+]
• mmu-mir-669a-6: chr2: 10484196-10484282 [+]
• mmu-mir-467a-4: chr2: 10486135-10486217 [+]

Database links

• ENTREZGENE: 735286;Mir467a-1
• MGI: 3629612;Mirn467a

Mature sequence mmu-miR-467a-5p

• Accession: MIMAT0003409
• Previous IDs: mmu-miR-467*;mmu-miR-467a
• Sequence: 10 - uaagugccugcauguauaugcg - 31
• Deep sequencing: 177369 reads, 75 experiments
• Evidence: experimental; MPSS [2], cloned [3], Solexa [4-5]
• Predicted targets:
  • DIANA-MICROT:mmu-miR-467a-5p
  • MICRORNA.ORG:mmu-miR-467a-5p
  • MIRDB:mmu-miR-467a-5p
  • RNA22-MMU:mmu-miR-467a-5p
  • TARGETSCAN-VERT:mmu-miR-467a

Mature sequence mmu-miR-467a-3p

• Accession: MIMAT0002108
• Previous IDs: mmu-miR-467;mmu-miR-467a;mmu-miR-467a*;mmu-miR-467a-1*;mmu-miR-467a*
• Sequence: 45 - cauauacauacacacaccuaca - 66
• Deep sequencing: 20983 reads, 71 experiments
• Evidence: experimental; cloned [1-3], Solexa [4-5]
• Predicted targets:
  • DIANA-MICROT:mmu-miR-467a-3p
  • MICRORNA.ORG:mmu-miR-467a-3p
  • MIRDB:mmu-miR-467a-3p
  • RNA22-MMU:mmu-miR-467a-3p

References

1. PMID:15901636 "MicroRNA Mirn122a reduces expression of the posttranscriptionally regulated germ cell transition protein 2 (Tnp2) messenger RNA (mRNA) by mRNA cleavage" Yu Z, Raabe T, Hecht NB Biol Reprod. 73:427-433(2005).
2. PMID:16582102 "The expression profile of microRNAs in mouse embryos" Mineno J, Okamoto S, Ando T, Sato M, Chono H, Izu H, Takayama M, Asada K, Mirochnitchenko O, Inouye M, Kato I Nucleic Acids Res. 34:1765-1771(2006).
3. PMID:17604727 "A mammalian microRNA expression atlas based on small RNA library sequencing" Landgraf P, Rusu M, Sheridan R, Sewer A, Iovino N, Aravin A, Pfeffer S, Rice A, Kamphorst AO, Landthaler M, Lin C, Socci ND, Hermida L, Fulci V, Chiaretti S, Foa R, Schliwka J, Fuchs U, Novosel A, Muller RU, Schermer B, Bissels U, Inman J, Phan Q, Chien M Cell. 129:1401-1414(2007).
4. PMID:20215419 "MicroRNA transcriptome in the newborn mouse ovaries determined by massive parallel sequencing" Ahn HW, Morin RD, Zhao H, Harris RA, Coarfa C, Chen ZJ, Milosavljevic A, Marra MA, Rajkovic A Mol Hum Reprod. 16:463-471(2010).
5. PMID:20413612 "Mammalian microRNAs: experimental evaluation of novel and previously annotated genes" Chiang HR, Schoenfeld LW, Ruby JG, Auyeung VC, Spies N, Baek D, Johnston WK, Russ C, Luo S, Babiarz JE, Blelloch R, Schroth GP, Nusbaum C, Bartel DP Genes Dev. 24:992-1009(2010).