Stem-loop sequence sof-MIR156

AccessionMI0001754 (change log)
DescriptionSaccharum officinarum miR156 stem-loop
Gene family MIPF0000008; MIR156
Community annotation

This text is a summary paragraph taken from the Wikipedia entry entitled mir-156_microRNA_precursor. miRBase and Rfam are facilitating community annotation of microRNA families and entries in Wikipedia. Read more ...

MicroRNA (miRNA) precursor mir-156 is a family of plant non-coding RNA. This microRNA has now been predicted or experimentally confirmed in a range of plant species (MIPF0000008). Animal miRNAs are transcribed as ~70 nucleotide precursors and subsequently processed by the Dicer enzyme to give a ~22 nucleotide product. In plants the precursor sequences may be longer, and the carpel factory (caf) enzyme appears to be involved in processing. In this case the mature sequence comes from the 5' arm of the precursor, and both Arabidopsis thaliana and rice genomes contain a number of related miRNA precursors which give rise to almost identical mature sequences. The extents of the hairpin precursors are not generally known and are estimated based on hairpin prediction. The products are thought to have regulatory roles through complementarity to mRNA.

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   ggu     a   --gugga          -     -        a      gccu   uu      ugaacg   g 
5'    ggaga gag       ggcugacaga agaga gugagcac cauggu    uuc  gcauga      auc a
      ||||| |||       |||||||||| ||||| |||||||| ||||||    |||  ||||||      |||  
3'    ucucu cuc       ccgacugucu ucucu cacucgug guaucg    aag  cguacu      ugg g
   --c     -   aagauug          c     u        c      ----   cu      ------   a 
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Database links

Mature sequence sof-miR156

Accession MIMAT0001656

21 - 


 - 40

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Evidence by similarity; MI0000654


PMID:15916721 "Identification and characterization of new plant microRNAs using EST analysis" Zhang BH, Pan XP, Wang QL, Cobb GP, Anderson TA Cell Res. 15:336-360(2005).
"Conservation and divergence of microRNA families in plants" Dezulian T, Palatnik JF, Huson DH, Weigel D (2005).