Stem-loop sequence hsa-mir-409

Accession

MI0001735

Symbol

HGNC:MIR409

Description

Homo sapiens miR-409 stem-loop

Gene family

MIPF0000018; mir-154

Stem-loop

u     u  gg   a    ac         -    - auc 
 gguac cg  gag gguu  ccgagcaac uuug c   u
 ||||| ||  ||| ||||  ||||||||| |||| |    
 cuaug gc  uuc ccaa  ggcucguug aagc g   g
a     -  uu   c    gu         u    a cag 

Deep sequencing

896 reads, 14 experiments

Comments

The mature sequence shown here represents the most commonly cloned form from large-scale cloning studies [4]. The 5' end of the miRNA may be offset with respect to previous annotations.

Genome context

• Coordinates (GRCh37.p5): chr14: 101531637-101531715 [+]
• Overlapping transcripts:

  intergenic

Clustered miRNAs

< 10kb from hsa-mir-409

• hsa-mir-485: chr14: 101521756-101521828 [+]
• hsa-mir-323b: chr14: 101522556-101522637 [+]
• hsa-mir-154: chr14: 101526092-101526175 [+]
• hsa-mir-496: chr14: 101526910-101527011 [+]
• hsa-mir-377: chr14: 101528387-101528455 [+]
• hsa-mir-541: chr14: 101530832-101530915 [+]
• hsa-mir-409: chr14: 101531637-101531715 [+]
• hsa-mir-412: chr14: 101531784-101531874 [+]
• hsa-mir-369: chr14: 101531935-101532004 [+]
• hsa-mir-410: chr14: 101532249-101532328 [+]
• hsa-mir-656: chr14: 101533061-101533138 [+]

Database links

• ENTREZGENE: 574413;MIR409
• HGNC: 32055;MIR409

Mature sequence hsa-miR-409-5p

• Accession: MIMAT0001638
• Sequence: 15 - agguuacccgagcaacuuugcau - 37
• Deep sequencing: 225 reads, 11 experiments
• Evidence: experimental; cloned [1,3-4]
• Predicted targets:
  • DIANA-MICROT:hsa-miR-409-5p
  • MICRORNA.ORG:hsa-miR-409-5p
  • MIRDB:hsa-miR-409-5p
  • RNA22-HSA:hsa-miR-409-5p
  • TARGETMINER:hsa-miR-409-5p
  • TARGETSCAN-VERT:hsa-miR-409-5p

Mature sequence hsa-miR-409-3p

• Accession: MIMAT0001639
• Sequence: 47 - gaauguugcucggugaaccccu - 68
• Deep sequencing: 671 reads, 5 experiments
• Evidence: experimental; cloned [1,3-4], array-cloned [2]
• Validated targets:
  • MIRTARBASE:hsa-miR-409-3p
  • TARBASE:hsa-miR-409-3p
• Predicted targets:
  • DIANA-MICROT:hsa-miR-409-3p
  • MICRORNA.ORG:hsa-miR-409-3p
  • MIRDB:hsa-miR-409-3p
  • RNA22-HSA:hsa-miR-409-3p
  • TARGETMINER:hsa-miR-409-3p
  • TARGETSCAN-VERT:hsa-miR-409-3p

References

1. PMID:15891114 "Clustering and conservation patterns of human microRNAs" Altuvia Y, Landgraf P, Lithwick G, Elefant N, Pfeffer S, Aravin A, Brownstein MJ, Tuschl T, Margalit H Nucleic Acids Res. 33:2697-2706(2005).
2. PMID:15965474 "Identification of hundreds of conserved and nonconserved human microRNAs" Bentwich I, Avniel A, Karov Y, Aharonov R, Gilad S, Barad O, Barzilai A, Einat P, Einav U, Meiri E, Sharon E, Spector Y, Bentwich Z Nat Genet. 37:766-770(2005).
3. PMID:16274478 "Identification of clustered microRNAs using an ab initio prediction method" Sewer A, Paul N, Landgraf P, Aravin A, Pfeffer S, Brownstein MJ, Tuschl T, van Nimwegen E, Zavolan M BMC Bioinformatics. 6:267(2005).
4. PMID:17604727 "A mammalian microRNA expression atlas based on small RNA library sequencing" Landgraf P, Rusu M, Sheridan R, Sewer A, Iovino N, Aravin A, Pfeffer S, Rice A, Kamphorst AO, Landthaler M, Lin C, Socci ND, Hermida L, Fulci V, Chiaretti S, Foa R, Schliwka J, Fuchs U, Novosel A, Muller RU, Schermer B, Bissels U, Inman J, Phan Q, Chien M Cell. 129:1401-1414(2007).