Stem-loop sequence sbi-MIR156c

AccessionMI0001505 (change log)
DescriptionSorghum bicolor miR156c stem-loop
Gene family MIPF0000008; MIR156
Community annotation

This text is a summary paragraph taken from the Wikipedia entry entitled mir-156_microRNA_precursor. miRBase and Rfam are facilitating community annotation of microRNA families and entries in Wikipedia. Read more ...

MicroRNA (miRNA) precursor mir-156 is a family of plant non-coding RNA. This microRNA has now been predicted or experimentally confirmed in a range of plant species (MIPF0000008). Animal miRNAs are transcribed as ~70 nucleotide precursors and subsequently processed by the Dicer enzyme to give a ~22 nucleotide product. In plants the precursor sequences may be longer, and the carpel factory (caf) enzyme appears to be involved in processing. In this case the mature sequence comes from the 5' arm of the precursor, and both Arabidopsis thaliana and rice genomes contain a number of related miRNA precursors which give rise to almost identical mature sequences. The extents of the hairpin precursors are not generally known and are estimated based on hairpin prediction. The products are thought to have regulatory roles through complementarity to mRNA.

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   u      -     -        a      gccu   uu      ugaau 
5'  gacaga agaga gugagcac cauggu    uuc  gcauga     g
    |||||| ||||| |||||||| ||||||    |||  ||||||     a
3'  cugucu ucucu cacucgug guaucg    aag  cguacu     g
   a      c     u        c      ----   cu      uaggu 
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Genome context
Coordinates (Sorghum_bicolor_NCBIv3; GCA_000003195.3) Overlapping transcripts
chr3: 3416227-3416321 [-]
Clustered miRNAs
< 10kb from sbi-MIR156c
sbi-MIR156cchr3: 3416227-3416321 [-]
sbi-MIR156bchr3: 3415906-3415989 [-]
Database links

Mature sequence sbi-miR156c

Accession MIMAT0001399

1 - 


 - 20

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Evidence by similarity; MI0000182


"Identifying microRNAs in plant genomes" Maher C, Timmermans M, Stein L, Ware D Proc IEEE CSB :718-723(2004).
PMID:15660154 "Sorghum genome sequencing by methylation filtration" Bedell JA, Budiman MA, Nunberg A, Citek RW, Robbins D, Jones J, Flick E, Rholfing T, Fries J, Bradford K, McMenamy J, Smith M, Holeman H, Roe BA, Wiley G, Korf IF, Rabinowicz PD, Lakey N, McCombie WR, Jeddeloh JA, Martienssen RA PLoS Biol. 3:e13(2005).