Stem-loop sequence hsa-mir-379

Accession

MI0000787

Symbol

HGNC:MIR379

Description

Homo sapiens miR-379 stem-loop

Gene family

MIPF0000126; mir-379

Stem-loop

    a    a       ga       -  uu u 
agag uggu gacuaug  acguagg cg  a g
|||| |||| |||||||  ||||||| ||  |  
ucuc auca cugguac  uguaucc gu  u a
    a    c       aa       a  cu u 

Deep sequencing

854 reads, 19 experiments

Comments

The mature sequence shown here represents the most commonly cloned form from large-scale cloning studies [4].

Genome context

• Coordinates (GRCh37.p5): chr14: 101488403-101488469 [+]
• Overlapping transcripts:

  sense

  ENST00000362218 ; MIR379-201; exon 1

Clustered miRNAs

< 10kb from hsa-mir-379

• hsa-mir-379: chr14: 101488403-101488469 [+]
• hsa-mir-411: chr14: 101489662-101489757 [+]
• hsa-mir-299: chr14: 101490131-101490193 [+]
• hsa-mir-380: chr14: 101491354-101491414 [+]
• hsa-mir-1197: chr14: 101491901-101491988 [+]
• hsa-mir-323a: chr14: 101492069-101492154 [+]
• hsa-mir-758: chr14: 101492357-101492444 [+]
• hsa-mir-329-1: chr14: 101493122-101493201 [+]
• hsa-mir-329-2: chr14: 101493437-101493520 [+]
• hsa-mir-494: chr14: 101495971-101496051 [+]
• hsa-mir-1193: chr14: 101496389-101496466 [+]
• hsa-mir-543: chr14: 101498324-101498401 [+]

Database links

• EMBL: AY882324;AY882324
• ENTREZGENE: 494328;MIR379
• HGNC: 31872;MIR379

Mature sequence hsa-miR-379-5p

• Accession: MIMAT0000733
• Previous IDs: hsa-miR-379
• Sequence: 6 - ugguagacuauggaacguagg - 26
• Deep sequencing: 686 reads, 12 experiments
• Evidence: experimental; cloned [2-4]
• Predicted targets:
  • DIANA-MICROT:hsa-miR-379-5p
  • MICRORNA.ORG:hsa-miR-379-5p
  • MIRDB:hsa-miR-379-5p
  • RNA22-HSA:hsa-miR-379-5p
  • TARGETMINER:hsa-miR-379-5p
  • TARGETSCAN-VERT:hsa-miR-379
  • PICTAR-VERT:hsa-miR-379

Mature sequence hsa-miR-379-3p

• Accession: MIMAT0004690
• Previous IDs: hsa-miR-379*
• Sequence: 44 - uauguaacaugguccacuaacu - 65
• Deep sequencing: 168 reads, 8 experiments
• Evidence: experimental; cloned [4]
• Predicted targets:
  • DIANA-MICROT:hsa-miR-379-3p
  • MICRORNA.ORG:hsa-miR-379-3p
  • MIRDB:hsa-miR-379-3p
  • RNA22-HSA:hsa-miR-379-3p
  • TARGETMINER:hsa-miR-379-3p
  • PICTAR-VERT:hsa-miR-379

References

1. PMID:15538371 "A pancreatic islet-specific microRNA regulates insulin secretion" Poy MN, Eliasson L, Krutzfeldt J, Kuwajima S, Ma X, Macdonald PE, Pfeffer S, Tuschl T, Rajewsky N, Rorsman P, Stoffel M Nature. 432:226-230(2004).
2. PMID:15891114 "Clustering and conservation patterns of human microRNAs" Altuvia Y, Landgraf P, Lithwick G, Elefant N, Pfeffer S, Aravin A, Brownstein MJ, Tuschl T, Margalit H Nucleic Acids Res. 33:2697-2706(2005).
3. PMID:16274478 "Identification of clustered microRNAs using an ab initio prediction method" Sewer A, Paul N, Landgraf P, Aravin A, Pfeffer S, Brownstein MJ, Tuschl T, van Nimwegen E, Zavolan M BMC Bioinformatics. 6:267(2005).
4. PMID:17604727 "A mammalian microRNA expression atlas based on small RNA library sequencing" Landgraf P, Rusu M, Sheridan R, Sewer A, Iovino N, Aravin A, Pfeffer S, Rice A, Kamphorst AO, Landthaler M, Lin C, Socci ND, Hermida L, Fulci V, Chiaretti S, Foa R, Schliwka J, Fuchs U, Novosel A, Muller RU, Schermer B, Bissels U, Inman J, Phan Q, Chien M Cell. 129:1401-1414(2007).