Stem-loop sequence rno-mir-151

AccessionMI0000647 (change log)
DescriptionRattus norvegicus miR-151 stem-loop
Gene family MIPF0000057; mir-28
Stem-loop
   --------------a   cu      c            ca          u uc 
5'                gcg  uuccug ccucgaggagcu  cagucuagua g  u
                  |||  |||||| ||||||||||||  |||||||||| |  c
3'                ugc  agggac ggaguuccucgg  gucagaucau c  c
   gcccuccacucauac   -u      a            -a          c cu 
Get sequence
Deep sequencing
263185 reads, 2.16e+03 reads per million, 39 experiments
Confidence Annotation confidence: high
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Comments

Kim et al. cloned 40 new miRNAs from rat E18 primary cortical neurons [1]. Landgraf et al show that the 5' product is the predominant one [3]. The mature sequence shown here represents the most commonly cloned form from large-scale cloning studies [3]. The ends of the miRNA may be offset with respect to previous annotations.

Genome context
Coordinates (Rnor_6.0; GCA_000001895.4) Overlapping transcripts
chr7: 114485547-114485643 [-]
sense
ENSRNOT00000011219 ; Ptk2-201; intron 21
antisense
ENSRNOT00000053580 ; Mir3586-201; exon 1
Clustered miRNAs
< 10kb from rno-mir-151
rno-mir-3586chr7: 114485547-114485666 [+]
rno-mir-151chr7: 114485547-114485643 [-]
Database links

Mature sequence rno-miR-151-5p

Accession MIMAT0000613
Previous IDsrno-miR-151*;rno-miR-151
Sequence

16 - 

ucgaggagcucacagucuagu

 - 36

Get sequence
Deep sequencing85665 reads, 39 experiments
Evidence experimental; cloned [1-3], SOLiD [4]
Predicted targets

Mature sequence rno-miR-151-3p

Accession MIMAT0000614
Previous IDsrno-miR-151;rno-miR-151*
Sequence

51 - 

cuagacugaggcuccuugagg

 - 71

Get sequence
Deep sequencing177520 reads, 39 experiments
Evidence experimental; cloned [3], SOLiD [4]
Predicted targets

References

1
PMID:14691248 "Identification of many microRNAs that copurify with polyribosomes in mammalian neurons" Kim J, Krichevsky A, Grad Y, Hayes GD, Kosik KS, Church GM, Ruvkun G Proc Natl Acad Sci U S A. 101:360-365(2004).
2
3
PMID:17604727 "A mammalian microRNA expression atlas based on small RNA library sequencing" Landgraf P, Rusu M, Sheridan R, Sewer A, Iovino N, Aravin A, Pfeffer S, Rice A, Kamphorst AO, Landthaler M, Lin C, Socci ND, Hermida L, Fulci V, Chiaretti S, Foa R, Schliwka J, Fuchs U, Novosel A, Muller RU, Schermer B, Bissels U, Inman J, Phan Q, Chien M Cell. 129:1401-1414(2007).
4
PMID:20403161 "Small RNA expression and strain specificity in the rat" Linsen SE, de Wit E, de Bruijn E, Cuppen E BMC Genomics. 11:249(2010).