Stem-loop sequence mmu-mir-27a

Symbol MGI:Mir27a
DescriptionMus musculus miR-27a stem-loop
Gene family MIPF0000036; mir-27
Community annotation

This text is a summary paragraph taken from the Wikipedia entry entitled miR-27. miRBase and Rfam are facilitating community annotation of microRNA families and entries in Wikipedia. Read more ...

miR-27 is a family of microRNA precursors found in animals, including humans. MicroRNAs are typically transcribed as ~70 nucleotide precursors and subsequently processed by the Dicer enzyme to give a ~22 nucleotide product. The excised region or, mature product, of the miR-27 precursor is the microRNA mir-27. Herpesvirus saimiri expresses several non-coding RNAs (HSURs) which have been found to significantly reduce the level of mir-27 in a host cell. It has been proposed that miR-27 operates together with miR-23 and mir-24 in a co-operative cluster.

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5'  gg cc g gg gc gggcuuagc  cu gugagca gg     a
    || || | || || |||||||||  || ||||||| ||      
3'  cc gg c cc cg cuugaaucg  ga cacuugu cu     g
   c  a  u -  c  c         gu  -       g  gaaac 
Get sequence
Deep sequencing
1238659 reads, 7.71e+03 reads per million, 108 experiments
Confidence Annotation confidence: high
Feedback: Do you believe this miRNA is real?
Genome context
Coordinates (GRCm38) Overlapping transcripts
chr8: 84208672-84208758 [+]
Clustered miRNAs
< 10kb from mmu-mir-27a
mmu-mir-23achr8: 84208518-84208592 [+]
mmu-mir-27achr8: 84208672-84208758 [+]
mmu-mir-24-2chr8: 84208815-84208921 [+]
mmu-mir-3074-2chr8: 84208825-84208907 [-]
Database links

Mature sequence mmu-miR-27a-5p

Accession MIMAT0004633
Previous IDsmmu-miR-27a*

14 - 


 - 35

Get sequence
Deep sequencing2765 reads, 82 experiments
Evidence experimental; cloned [5], Illumina [6-7]
Predicted targets

Mature sequence mmu-miR-27a-3p

Accession MIMAT0000537
Previous IDsmmu-miR-27a

56 - 


 - 76

Get sequence
Deep sequencing523307 reads, 90 experiments
Evidence experimental; cloned [1-2,4-5], Northern [1], Illumina [6]
Validated targets
Predicted targets


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PMID:20413612 "Mammalian microRNAs: experimental evaluation of novel and previously annotated genes" Chiang HR, Schoenfeld LW, Ruby JG, Auyeung VC, Spies N, Baek D, Johnston WK, Russ C, Luo S, Babiarz JE, Blelloch R, Schroth GP, Nusbaum C, Bartel DP Genes Dev. 24:992-1009(2010).