Stem-loop sequence hsa-mir-140

Symbol HGNC:MIR140
DescriptionHomo sapiens miR-140 stem-loop
Gene family MIPF0000085; mir-140
   u       ucucu        -  a             a       uu   uc 
5'  gugucuc     guguccug cc gugguuuuacccu ugguagg  acg  a
    |||||||     |||||||| || ||||||||||||| |||||||  |||   
3'  cacgggg     cauaggac gg caccaagauggga accaucu  ugu  u
   c       ----c        a  -             c       --   cg 
Get sequence
Deep sequencing
348775 reads, 9.46e+03 reads per million, 75 experiments
Confidence Annotation confidence: high
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This miRNA sequence is predicted based on homology to a verified miRNA from mouse [1]. Its expression was later verified in human [2,3]. The mature sequence shown here represents the most commonly cloned form from large-scale cloning studies [3]. The 5' end of the miRNA may be offset with respect to previous annotations.

Genome context
Coordinates (GRCh38) Overlapping transcripts
chr16: 69933081-69933180 [+]
OTTHUMT00000434486 ; WWP2-011; intron 1
OTTHUMT00000434487 ; WWP2-013; intron 1
OTTHUMT00000434485 ; WWP2-010; intron 2
OTTHUMT00000434482 ; WWP2-002; intron 6
OTTHUMT00000268954 ; WWP2-001; intron 8
OTTHUMT00000434481 ; WWP2-012; intron 8
ENST00000569297 ; WWP2-011; intron 1
ENST00000567579 ; WWP2-013; intron 1
ENST00000570104 ; WWP2-010; intron 2
ENST00000542271 ; WWP2-203; intron 5
ENST00000544162 ; WWP2-002; intron 6
ENST00000356003 ; WWP2-201; intron 7
ENST00000359154 ; WWP2-001; intron 8
ENST00000569174 ; WWP2-012; intron 8
ENST00000448661 ; WWP2-202; intron 8
Database links

Mature sequence hsa-miR-140-5p

Accession MIMAT0000431
Previous IDshsa-miR-140

23 - 


 - 44

Get sequence
Deep sequencing563 reads, 49 experiments
Evidence experimental; cloned [2-3]
Validated targets
Predicted targets

Mature sequence hsa-miR-140-3p

Accession MIMAT0004597

62 - 


 - 82

Get sequence
Deep sequencing29357 reads, 63 experiments
Evidence experimental; cloned [3-4]
Validated targets
Predicted targets


PMID:12007417 "Identification of tissue-specific microRNAs from mouse" Lagos-Quintana M, Rauhut R, Yalcin A, Meyer J, Lendeckel W, Tuschl T Curr Biol. 12:735-739(2002).
PMID:15800047 "Kaposi's sarcoma-associated herpesvirus expresses an array of viral microRNAs in latently infected cells" Cai X, Lu S, Zhang Z, Gonzalez CM, Damania B, Cullen BR Proc Natl Acad Sci U S A. 102:5570-5575(2005).
PMID:17604727 "A mammalian microRNA expression atlas based on small RNA library sequencing" Landgraf P, Rusu M, Sheridan R, Sewer A, Iovino N, Aravin A, Pfeffer S, Rice A, Kamphorst AO, Landthaler M, Lin C, Socci ND, Hermida L, Fulci V, Chiaretti S, Foa R, Schliwka J, Fuchs U, Novosel A, Muller RU, Schermer B, Bissels U, Inman J, Phan Q, Chien M Cell. 129:1401-1414(2007).
PMID:17616659 "Patterns of known and novel small RNAs in human cervical cancer" Lui WO, Pourmand N, Patterson BK, Fire A Cancer Res. 67:6031-6043(2007).