Stem-loop sequence hsa-mir-133a-1

AccessionMI0000450 (change log)
Symbol HGNC:MIR133A1
DescriptionHomo sapiens miR-133a-1 stem-loop
Gene family MIPF0000029; mir-133
Literature search

384 open access papers mention hsa-mir-133a-1
(1775 sentences)

Stem-loop
   a      uuu    g       aa  u  a        gccuc 
5'  caaugc   gcua agcuggu  aa gg accaaauc     u
    ||||||   |||| |||||||  || || ||||||||      
3'  guuacg   cgau ucgacca  uu cc ugguuuag     u
   a      uau    g       ac  c  c        guaac 
Get sequence
Deep sequencing
296052 reads, 543 reads per million, 143 experiments
Confidence Annotation confidence: high
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Comments

This miRNA sequence is predicted based on homology to a verified miRNA from mouse [1], later verified in human [2].

Genome context
Coordinates (GRCh38; GCA_000001405.15) Overlapping transcripts
chr18: 21825698-21825785 [-]
sense
OTTHUMT00000254903 ; OSBPL1A-002; intron 1
OTTHUMT00000446405 ; OSBPL1A-015; intron 1
OTTHUMT00000446434 ; OSBPL1A-016; intron 1
OTTHUMT00000446357 ; OSBPL1A-003; intron 3
OTTHUMT00000446406 ; OSBPL1A-014; intron 4
OTTHUMT00000254902 ; OSBPL1A-001; intron 15
ENST00000399443 ; OSBPL1A-002; intron 1
ENST00000578055 ; OSBPL1A-015; intron 1
ENST00000585247 ; OSBPL1A-016; intron 1
ENST00000357041 ; OSBPL1A-003; intron 3
ENST00000584119 ; OSBPL1A-014; intron 4
ENST00000319481 ; OSBPL1A-001; intron 15
Clustered miRNAs
< 10kb from hsa-mir-133a-1
hsa-mir-1-2chr18: 21829004-21829088 [-]
hsa-mir-133a-1chr18: 21825698-21825785 [-]
Database links

Mature sequence hsa-miR-133a-5p

Accession MIMAT0026478
Sequence

16 - 

agcugguaaaauggaaccaaau

 - 37

Get sequence
Deep sequencing17566 reads, 117 experiments
Evidence experimental; Illumina [3]
Database links
Predicted targets

Mature sequence hsa-miR-133a-3p

Accession MIMAT0000427
Sequence

53 - 

uuugguccccuucaaccagcug

 - 74

Get sequence
Deep sequencing574422 reads, 143 experiments
Evidence experimental; cloned [2], Illumina [3]
Database links
Predicted targets

References

1
PMID:12007417 "Identification of tissue-specific microRNAs from mouse" Lagos-Quintana M, Rauhut R, Yalcin A, Meyer J, Lendeckel W, Tuschl T Curr Biol. 12:735-739(2002).
2
PMID:17604727 "A mammalian microRNA expression atlas based on small RNA library sequencing" Landgraf P, Rusu M, Sheridan R, Sewer A, Iovino N, Aravin A, Pfeffer S, Rice A, Kamphorst AO, Landthaler M, Lin C, Socci ND, Hermida L, Fulci V, Chiaretti S, Foa R, Schliwka J, Fuchs U, Novosel A, Muller RU, Schermer B, Bissels U, Inman J, Phan Q, Chien M Cell. 129:1401-1414(2007).
3
PMID:23034410 "Birth and expression evolution of mammalian microRNA genes" Meunier J, Lemoine F, Soumillon M, Liechti A, Weier M, Guschanski K, Hu H, Khaitovich P, Kaessmann H Genome Res. 23:34-45(2013).