Stem-loop sequence mmu-mir-186

Accession

MI0000228

Symbol

MGI:Mir186

Description

Mus musculus miR-186 stem-loop

Gene family

MIPF0000109; mir-186

Stem-loop

                u    uu      ucucau 
acuuuccaaagaauuc ccuu  gggcuu      u
|||||||||||||||| ||||  ||||||       
ugaaggguuuuuuaag ggaa  cccgaa      u
                u    -u      uuuuau 

Deep sequencing

567530 reads, 97 experiments

Comments

The mature sequence shown here represents the most commonly cloned form from large-scale cloning studies [3].

Genome context

• Coordinates (GRCm38): chr3: 157544279-157544349 [+]
• Overlapping transcripts:

  sense

  OTTMUST00000040347 ; Zranb2-004; intron 7

  OTTMUST00000040346 ; Zranb2-003; intron 7

  OTTMUST00000040345 ; Zranb2-002; intron 8

  OTTMUST00000040344 ; Zranb2-001; intron 8

  ENSMUST00000152882 ; Zranb2-004; intron 7

  ENSMUST00000136928 ; Zranb2-003; intron 7

  ENSMUST00000106063 ; Zranb2-202; intron 8

  ENSMUST00000029831 ; Zranb2-201; intron 8

  ENSMUST00000106057 ; Zranb2-002; intron 8

  ENSMUST00000106058 ; Zranb2-001; intron 8

Database links

• EMBL: AJ560728;MMU560728
• ENTREZGENE: 387181;Mir186
• MGI: 2676850;Mir186

Mature sequence mmu-miR-186-5p

• Accession: MIMAT0000215
• Previous IDs: mmu-miR-186
• Sequence: 7 - caaagaauucuccuuuugggcu - 28
• Deep sequencing: 82957 reads, 82 experiments
• Evidence: experimental; cloned [1-3], Solexa [4-5]
• Predicted targets:
  • DIANA-MICROT:mmu-miR-186-5p
  • MICRORNA.ORG:mmu-miR-186-5p
  • MIRDB:mmu-miR-186-5p
  • RNA22-MMU:mmu-miR-186-5p
  • TARGETSCAN-VERT:mmu-miR-186

Mature sequence mmu-miR-186-3p

• Accession: MIMAT0004540
• Previous IDs: mmu-miR-186*
• Sequence: 46 - gcccuaaggugaauuuuuuggg - 67
• Deep sequencing: 1738 reads, 79 experiments
• Evidence: experimental; cloned [3], Solexa [4-5]
• Predicted targets:
  • DIANA-MICROT:mmu-miR-186-3p
  • MICRORNA.ORG:mmu-miR-186-3p
  • MIRDB:mmu-miR-186-3p
  • RNA22-MMU:mmu-miR-186-3p

References

1. PMID:12554859 "New microRNAs from mouse and human" Lagos-Quintana M, Rauhut R, Meyer J, Borkhardt A, Tuschl T RNA. 9:175-179(2003).
2. PMID:12554860 "Numerous microRNPs in neuronal cells containing novel microRNAs" Dostie J, Mourelatos Z, Yang M, Sharma A, Dreyfuss G RNA. 9:180-186(2003).
3. PMID:17604727 "A mammalian microRNA expression atlas based on small RNA library sequencing" Landgraf P, Rusu M, Sheridan R, Sewer A, Iovino N, Aravin A, Pfeffer S, Rice A, Kamphorst AO, Landthaler M, Lin C, Socci ND, Hermida L, Fulci V, Chiaretti S, Foa R, Schliwka J, Fuchs U, Novosel A, Muller RU, Schermer B, Bissels U, Inman J, Phan Q, Chien M Cell. 129:1401-1414(2007).
4. PMID:20215419 "MicroRNA transcriptome in the newborn mouse ovaries determined by massive parallel sequencing" Ahn HW, Morin RD, Zhao H, Harris RA, Coarfa C, Chen ZJ, Milosavljevic A, Marra MA, Rajkovic A Mol Hum Reprod. 16:463-471(2010).
5. PMID:20413612 "Mammalian microRNAs: experimental evaluation of novel and previously annotated genes" Chiang HR, Schoenfeld LW, Ruby JG, Auyeung VC, Spies N, Baek D, Johnston WK, Russ C, Luo S, Babiarz JE, Blelloch R, Schroth GP, Nusbaum C, Bartel DP Genes Dev. 24:992-1009(2010).