Stem-loop sequence mmu-mir-182

Accession

MI0000224

Symbol

MGI:Mir182

Description

Mus musculus miR-182 stem-loop

Gene family

MIPF0000116; mir-182

Stem-loop

     uu       u -g      uca      uaaggu 
accau  uuggcaa g  uagaac   caccgg      a
|||||  ||||||| |  ||||||   ||||||       
uggua  aaccguu c  aucuug   guggcc      a
     uc       - ag      ---      cagggu 

Deep sequencing

96248 reads, 94 experiments

Comments

The mature sequence shown here represents the most commonly cloned form from large-scale cloning studies [3].

Genome context

• Coordinates (GRCm38): chr6: 30165918-30165992 [-]
• Overlapping transcripts:

  intergenic

Clustered miRNAs

< 10kb from mmu-mir-182

• mmu-mir-183: chr6: 30169668-30169737 [-]
• mmu-mir-96: chr6: 30169446-30169551 [-]
• mmu-mir-182: chr6: 30165918-30165992 [-]

Database links

• EMBL: AJ560724;MMU560724
• ENTREZGENE: 387177;Mir182
• MGI: 2676846;Mir182

Mature sequence mmu-miR-182-5p

• Accession: MIMAT0000211
• Previous IDs: mmu-miR-182
• Sequence: 7 - uuuggcaaugguagaacucacaccg - 31
• Deep sequencing: 48273 reads, 79 experiments
• Evidence: experimental; cloned [1-3], Solexa [4,6]
• Predicted targets:
  • DIANA-MICROT:mmu-miR-182-5p
  • MICRORNA.ORG:mmu-miR-182-5p
  • MIRDB:mmu-miR-182-5p
  • RNA22-MMU:mmu-miR-182-5p
  • TARGETSCAN-VERT:mmu-miR-182

Mature sequence mmu-miR-182-3p

• Accession: MIMAT0016995
• Previous IDs: mmu-miR-182*
• Sequence: 50 - gugguucuagacuugccaacu - 70
• Deep sequencing: 293 reads, 38 experiments
• Evidence: experimental; 454 [5], Solexa [6]
• Predicted targets:
  • DIANA-MICROT:mmu-miR-182-3p
  • MIRDB:mmu-miR-182-3p
  • RNA22-MMU:mmu-miR-182-3p

References

1. PMID:12554859 "New microRNAs from mouse and human" Lagos-Quintana M, Rauhut R, Meyer J, Borkhardt A, Tuschl T RNA. 9:175-179(2003).
2. PMID:15538371 "A pancreatic islet-specific microRNA regulates insulin secretion" Poy MN, Eliasson L, Krutzfeldt J, Kuwajima S, Ma X, Macdonald PE, Pfeffer S, Tuschl T, Rajewsky N, Rorsman P, Stoffel M Nature. 432:226-230(2004).
3. PMID:17604727 "A mammalian microRNA expression atlas based on small RNA library sequencing" Landgraf P, Rusu M, Sheridan R, Sewer A, Iovino N, Aravin A, Pfeffer S, Rice A, Kamphorst AO, Landthaler M, Lin C, Socci ND, Hermida L, Fulci V, Chiaretti S, Foa R, Schliwka J, Fuchs U, Novosel A, Muller RU, Schermer B, Bissels U, Inman J, Phan Q, Chien M Cell. 129:1401-1414(2007).
4. PMID:20215419 "MicroRNA transcriptome in the newborn mouse ovaries determined by massive parallel sequencing" Ahn HW, Morin RD, Zhao H, Harris RA, Coarfa C, Chen ZJ, Milosavljevic A, Marra MA, Rajkovic A Mol Hum Reprod. 16:463-471(2010).
5. PMID:20668074 "Identification and analysis of expression of novel microRNAs of murine gammaherpesvirus 68" Zhu JY, Strehle M, Frohn A, Kremmer E, Hofig KP, Meister G, Adler H J Virol. 84:10266-10275(2010).
6. PMID:20413612 "Mammalian microRNAs: experimental evaluation of novel and previously annotated genes" Chiang HR, Schoenfeld LW, Ruby JG, Auyeung VC, Spies N, Baek D, Johnston WK, Russ C, Luo S, Babiarz JE, Blelloch R, Schroth GP, Nusbaum C, Bartel DP Genes Dev. 24:992-1009(2010).