Stem-loop sequence mmu-mir-155

AccessionMI0000177
Symbol MGI:Mir155
DescriptionMus musculus miR-155 stem-loop
Gene family MIPF0000157; mir-155
Community annotation

This text is a summary paragraph taken from the Wikipedia entry entitled Mir-155. miRBase and Rfam are facilitating community annotation of microRNA families and entries in Wikipedia. Read more ...

MiR-155 is a microRNA that in humans is encoded by the MIR155 host gene or MIR155HG. MiR-155 plays an important role in various physiological and pathological processes. Exogenous molecular control in vivo of miR-155 expression may inhibit malignant growth, viral infections, and attenuate the progression of cardiovascular diseases.

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Stem-loop
                 ugu a        uu gcc 
5' cuguuaaugcuaau   g uagggguu  g   u
   ||||||||||||||   | ||||||||  |    
3' gacaauuacgauug   c auccucag  c   c
                 --u c        -u agu 
Get sequence
Deep sequencing
114653 reads, 500 reads per million, 99 experiments
Confidence Annotation confidence: high
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Comments

Mouse mir-155 resides in the non-coding BIC transcript (EMBL:AY096003), located on chromosome 16 [2]. The mature sequence shown here represents the most commonly cloned form from large-scale cloning studies [3].

Genome context
Coordinates (GRCm38) Overlapping transcripts
chr16: 84714140-84714204 [+]
sense
ENSMUST00000180991 ; Gm26667-201; exon 2
Database links

Mature sequence mmu-miR-155-5p

Accession MIMAT0000165
Previous IDsmmu-miR-155
Sequence

4 - 

uuaaugcuaauugugauaggggu

 - 26

Get sequence
Deep sequencing97966 reads, 85 experiments
Evidence experimental; cloned [1,3], Illumina [5]
Validated targets
Predicted targets

Mature sequence mmu-miR-155-3p

Accession MIMAT0016993
Previous IDsmmu-miR-155*
Sequence

43 - 

cuccuaccuguuagcauuaac

 - 63

Get sequence
Deep sequencing2041 reads, 46 experiments
Evidence experimental; 454 [4], Illumina [5]
Predicted targets

References

1
PMID:12007417 "Identification of tissue-specific microRNAs from mouse" Lagos-Quintana M, Rauhut R, Yalcin A, Meyer J, Lendeckel W, Tuschl T Curr Biol. 12:735-739(2002).
2
3
PMID:17604727 "A mammalian microRNA expression atlas based on small RNA library sequencing" Landgraf P, Rusu M, Sheridan R, Sewer A, Iovino N, Aravin A, Pfeffer S, Rice A, Kamphorst AO, Landthaler M, Lin C, Socci ND, Hermida L, Fulci V, Chiaretti S, Foa R, Schliwka J, Fuchs U, Novosel A, Muller RU, Schermer B, Bissels U, Inman J, Phan Q, Chien M Cell. 129:1401-1414(2007).
4
PMID:20668074 "Identification and analysis of expression of novel microRNAs of murine gammaherpesvirus 68" Zhu JY, Strehle M, Frohn A, Kremmer E, Hofig KP, Meister G, Adler H J Virol. 84:10266-10275(2010).
5
PMID:20413612 "Mammalian microRNAs: experimental evaluation of novel and previously annotated genes" Chiang HR, Schoenfeld LW, Ruby JG, Auyeung VC, Spies N, Baek D, Johnston WK, Russ C, Luo S, Babiarz JE, Blelloch R, Schroth GP, Nusbaum C, Bartel DP Genes Dev. 24:992-1009(2010).