Stem-loop sequence mmu-mir-154

Accession

MI0000176

Symbol

MGI:Mir154

Description

Mus musculus miR-154 stem-loop

Gene family

MIPF0000018; mir-154

Stem-loop

            u      ugcc    - uuu 
gaagauagguua ccgugu    uucg c   a
|||||||||||| ||||||    |||| |   u
uuuuuauccagu ggcaca    aagc g   u
            u      uacu    a ugc 

Deep sequencing

reads, experiments

Genome context

• Coordinates (GRCm38): chr12: 109738433-109738498 [+]
• Overlapping transcripts:

  sense

  ENSMUST00000083514 ; Mir154-201; exon 1

Clustered miRNAs

< 10kb from mmu-mir-154

• mmu-mir-544: chr12: 109729325-109729402 [+]
• mmu-mir-382: chr12: 109733771-109733846 [+]
• mmu-mir-134: chr12: 109734139-109734209 [+]
• mmu-mir-668: chr12: 109734732-109734797 [+]
• mmu-mir-485: chr12: 109734902-109734974 [+]
• mmu-mir-453: chr12: 109735619-109735700 [+]
• mmu-mir-154: chr12: 109738433-109738498 [+]
• mmu-mir-496a: chr12: 109739119-109739197 [+]
• mmu-mir-377: chr12: 109740510-109740577 [+]
• mmu-mir-541: chr12: 109742409-109742498 [+]
• mmu-mir-409: chr12: 109743158-109743236 [+]
• mmu-mir-412: chr12: 109743289-109743368 [+]
• mmu-mir-369: chr12: 109743418-109743496 [+]
• mmu-mir-410: chr12: 109743715-109743795 [+]
• mmu-mir-3072: chr12: 109747878-109747960 [+]

Database links

• EMBL: AJ459766;MMU459766
• ENTREZGENE: 387172;Mir154
• MGI: 2676839;Mir154

Mature sequence mmu-miR-154-5p

• Accession: MIMAT0000164
• Previous IDs: mmu-miR-154
• Sequence: 6 - uagguuauccguguugccuucg - 27
• Evidence: experimental; cloned [1,3-4], PCR [2], Solexa [5-6]
• Predicted targets:
  • DIANA-MICROT:mmu-miR-154-5p
  • MICRORNA.ORG:mmu-miR-154-5p
  • MIRDB:mmu-miR-154-5p
  • RNA22-MMU:mmu-miR-154-5p
  • TARGETSCAN-VERT:mmu-miR-154

Mature sequence mmu-miR-154-3p

• Accession: MIMAT0004537
• Previous IDs: mmu-miR-154*
• Sequence: 42 - aaucauacacgguugaccuauu - 63
• Evidence: experimental; cloned [4], Solexa [5-6]
• Predicted targets:
  • DIANA-MICROT:mmu-miR-154-3p
  • MICRORNA.ORG:mmu-miR-154-3p
  • MIRDB:mmu-miR-154-3p
  • RNA22-MMU:mmu-miR-154-3p

References

1. PMID:12007417 "Identification of tissue-specific microRNAs from mouse" Lagos-Quintana M, Rauhut R, Yalcin A, Meyer J, Lendeckel W, Tuschl T Curr Biol. 12:735-739(2002).
2. PMID:15310658 "A large imprinted microRNA gene cluster at the mouse Dlk1-Gtl2 domain" Seitz H, Royo H, Bortolin ML, Lin SP, Ferguson-Smith AC, Cavaille J Genome Res. 14:1741-1748(2004).
3. PMID:15538371 "A pancreatic islet-specific microRNA regulates insulin secretion" Poy MN, Eliasson L, Krutzfeldt J, Kuwajima S, Ma X, Macdonald PE, Pfeffer S, Tuschl T, Rajewsky N, Rorsman P, Stoffel M Nature. 432:226-230(2004).
4. PMID:17604727 "A mammalian microRNA expression atlas based on small RNA library sequencing" Landgraf P, Rusu M, Sheridan R, Sewer A, Iovino N, Aravin A, Pfeffer S, Rice A, Kamphorst AO, Landthaler M, Lin C, Socci ND, Hermida L, Fulci V, Chiaretti S, Foa R, Schliwka J, Fuchs U, Novosel A, Muller RU, Schermer B, Bissels U, Inman J, Phan Q, Chien M Cell. 129:1401-1414(2007).
5. PMID:20215419 "MicroRNA transcriptome in the newborn mouse ovaries determined by massive parallel sequencing" Ahn HW, Morin RD, Zhao H, Harris RA, Coarfa C, Chen ZJ, Milosavljevic A, Marra MA, Rajkovic A Mol Hum Reprod. 16:463-471(2010).
6. PMID:20413612 "Mammalian microRNAs: experimental evaluation of novel and previously annotated genes" Chiang HR, Schoenfeld LW, Ruby JG, Auyeung VC, Spies N, Baek D, Johnston WK, Russ C, Luo S, Babiarz JE, Blelloch R, Schroth GP, Nusbaum C, Bartel DP Genes Dev. 24:992-1009(2010).