Stem-loop sequence mmu-mir-145a

Accession

MI0000169 (change log)

Previous IDs

mmu-mir-145

Symbol

MGI:Mir145a

Description

Mus musculus miR-145 stem-loop

Gene family

MIPF0000079; mir-145

Literature search

217 open access papers mention mmu-mir-145a
(1841 sentences)

Stem-loop

       c  uc    u  c            uggau 
5' cuca gg  cagu uu ccaggaaucccu     g
   |||| ||  |||| || ||||||||||||     c
3' gagu uc  guca aa gguccuuagggg     u
       -  uu    u  a            uagaa 

Deep sequencing

508298 reads, 1.33e+03 reads per million, 90 experiments

Confidence

Annotation confidence: high

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Comments

The mature sequence shown here represents the most commonly cloned form from large-scale cloning studies [2].

Genome context

• Coordinates (GRCm38; GCA_000001635.2): chr18: 61647825-61647894 [-]
• Overlapping transcripts:

  sense

  ENSMUST00000083658 ; Mir145-201; exon 1

Clustered miRNAs

< 10kb from mmu-mir-145a

• mmu-mir-143: chr18: 61649196-61649258 [-]
• mmu-mir-145a: chr18: 61647825-61647894 [-]

Database links

• EntrezGene:Mir145
• MGI:Mir145a
• RNAcentral:URS000075C4F5_10090
• miRBase Tracker:MI0000169

Mature sequence mmu-miR-145a-5p

• Accession: MIMAT0000157
• Previous IDs: mmu-miR-145;mmu-miR-145-5p
• Sequence: 7 - guccaguuuucccaggaaucccu - 29
• Deep sequencing: 421607 reads, 89 experiments
• Evidence: experimental; cloned [1-2], Illumina [3-4]
• Database links:
  • RNAcentral:URS0000527F89_10090
• Predicted targets:
  • TargetScanVert:mmu-miR-145a-5p
  • miRDB:mmu-miR-145a-5p
  • microrna.org:mmu-miR-145a-5p

Mature sequence mmu-miR-145a-3p

• Accession: MIMAT0004534
• Previous IDs: mmu-miR-145*;mmu-miR-145-3p
• Sequence: 47 - auuccuggaaauacuguucuug - 68
• Deep sequencing: 85302 reads, 79 experiments
• Evidence: experimental; cloned [2], Illumina [3-4]
• Database links:
  • RNAcentral:URS00002D3C42_10090
• Predicted targets:
  • TargetScanVert:mmu-miR-145a-3p
  • miRDB:mmu-miR-145a-3p
  • microrna.org:mmu-miR-145a-3p

References

1. PMID:12007417 "Identification of tissue-specific microRNAs from mouse" Lagos-Quintana M, Rauhut R, Yalcin A, Meyer J, Lendeckel W, Tuschl T Curr Biol. 12:735-739(2002).
2. PMID:17604727 "A mammalian microRNA expression atlas based on small RNA library sequencing" Landgraf P, Rusu M, Sheridan R, Sewer A, Iovino N, Aravin A, Pfeffer S, Rice A, Kamphorst AO, Landthaler M, Lin C, Socci ND, Hermida L, Fulci V, Chiaretti S, Foa R, Schliwka J, Fuchs U, Novosel A, Muller RU, Schermer B, Bissels U, Inman J, Phan Q, Chien M Cell. 129:1401-1414(2007).
3. PMID:20215419 "MicroRNA transcriptome in the newborn mouse ovaries determined by massive parallel sequencing" Ahn HW, Morin RD, Zhao H, Harris RA, Coarfa C, Chen ZJ, Milosavljevic A, Marra MA, Rajkovic A Mol Hum Reprod. 16:463-471(2010).
4. PMID:20413612 "Mammalian microRNAs: experimental evaluation of novel and previously annotated genes" Chiang HR, Schoenfeld LW, Ruby JG, Auyeung VC, Spies N, Baek D, Johnston WK, Russ C, Luo S, Babiarz JE, Blelloch R, Schroth GP, Nusbaum C, Bartel DP Genes Dev. 24:992-1009(2010).