Stem-loop sequence mmu-mir-140

Accession

MI0000165

Symbol

MGI:Mir140

Description

Mus musculus miR-140 stem-loop

Gene family

MIPF0000085; mir-140

Stem-loop

    -  a             a       uu   uc 
ccug cc gugguuuuacccu ugguagg  acg  a
|||| || ||||||||||||| |||||||  |||   
ggac gg caccaagauggga accaucu  ugu  u
    a  -             c       --   cg 

Deep sequencing

6918207 reads, 97 experiments

Genome context

• Coordinates (GRCm38): chr8: 107551244-107551313 [+]
• Overlapping transcripts:

  sense

  ENSMUST00000166615 ; Wwp2-201; intron 16

Database links

• EMBL: AJ459751;MMU459751
• ENTREZGENE: 387158;Mir140
• MGI: 2676825;Mir140

Mature sequence mmu-miR-140-5p

• Accession: MIMAT0000151
• Previous IDs: mmu-miR-140
• Sequence: 6 - cagugguuuuacccuaugguag - 27
• Deep sequencing: 92372 reads, 82 experiments
• Evidence: experimental; cloned [1-4], Solexa [5-6]
• Validated targets:
  • TARBASE:mmu-miR-140-5p
• Predicted targets:
  • DIANA-MICROT:mmu-miR-140-5p
  • MICRORNA.ORG:mmu-miR-140-5p
  • MIRDB:mmu-miR-140-5p
  • RNA22-MMU:mmu-miR-140-5p
  • TARGETSCAN-VERT:mmu-miR-140

Mature sequence mmu-miR-140-3p

• Accession: MIMAT0000152
• Previous IDs: mmu-miR-140*
• Sequence: 45 - uaccacaggguagaaccacgg - 65
• Deep sequencing: 6750005 reads, 82 experiments
• Evidence: experimental; cloned [2,4], Solexa [5-6]
• Predicted targets:
  • DIANA-MICROT:mmu-miR-140-3p
  • MICRORNA.ORG:mmu-miR-140-3p
  • MIRDB:mmu-miR-140-3p
  • RNA22-MMU:mmu-miR-140-3p

References

1. PMID:12007417 "Identification of tissue-specific microRNAs from mouse" Lagos-Quintana M, Rauhut R, Yalcin A, Meyer J, Lendeckel W, Tuschl T Curr Biol. 12:735-739(2002).
2. PMID:15538371 "A pancreatic islet-specific microRNA regulates insulin secretion" Poy MN, Eliasson L, Krutzfeldt J, Kuwajima S, Ma X, Macdonald PE, Pfeffer S, Tuschl T, Rajewsky N, Rorsman P, Stoffel M Nature. 432:226-230(2004).
3. PMID:16766679 "Identification and characterization of two novel classes of small RNAs in the mouse germline: retrotransposon-derived siRNAs in oocytes and germline small RNAs in testes" Watanabe T, Takeda A, Tsukiyama T, Mise K, Okuno T, Sasaki H, Minami N, Imai H Genes Dev. 20:1732-1743(2006).
4. PMID:17604727 "A mammalian microRNA expression atlas based on small RNA library sequencing" Landgraf P, Rusu M, Sheridan R, Sewer A, Iovino N, Aravin A, Pfeffer S, Rice A, Kamphorst AO, Landthaler M, Lin C, Socci ND, Hermida L, Fulci V, Chiaretti S, Foa R, Schliwka J, Fuchs U, Novosel A, Muller RU, Schermer B, Bissels U, Inman J, Phan Q, Chien M Cell. 129:1401-1414(2007).
5. PMID:20215419 "MicroRNA transcriptome in the newborn mouse ovaries determined by massive parallel sequencing" Ahn HW, Morin RD, Zhao H, Harris RA, Coarfa C, Chen ZJ, Milosavljevic A, Marra MA, Rajkovic A Mol Hum Reprod. 16:463-471(2010).
6. PMID:20413612 "Mammalian microRNAs: experimental evaluation of novel and previously annotated genes" Chiang HR, Schoenfeld LW, Ruby JG, Auyeung VC, Spies N, Baek D, Johnston WK, Russ C, Luo S, Babiarz JE, Blelloch R, Schroth GP, Nusbaum C, Bartel DP Genes Dev. 24:992-1009(2010).