Stem-loop sequence MI0000108

Accession

MI0000108

ID

hsa-mir-103-2

Symbol

HGNC:MIR103-2

Description

Homo sapiens miR-103-2 stem-loop

Stem-loop

uu  g      --   u  u           ----    ua 
  gu cuuuca  gcu cu uacagugcugc    cuug  g
  || ||||||  ||| || |||||||||||    ||||  c
  ca gaaagu  cgg ga auguuacgacg    ggac  a
ac  a      au   -  c           aacu    uu 

Comments

This sequence was localised to chromosome 20 and named mir-103-20 in reference [1].

Genome context

• Coordinates (GRCh37): 20: 3898141-3898218 [+]
• Overlapping transcripts:

  sense

  OTTHUMT00000077787 ; PANK2-001; intron 5

  OTTHUMT00000077788 ; PANK2-002; intron 5

  OTTHUMT00000077789 ; PANK2-003; intron 5

  OTTHUMT00000077793 ; PANK2-007; intron 5

  ENST00000336066 ; PANK2-001; intron 5

  ENST00000316562 ; PANK2-007; intron 5

  ENST00000361370 ; PANK2-201; intron 5

  ENST00000399552 ; PANK2-202; intron 5

View flanking features

Clustered miRNAs

< 10kb from hsa-mir-103-2

• hsa-mir-103-2: 20: 3898141-3898218 [+]
• hsa-mir-103-2-as: 20: 3898149-3898210 [-]

Database links

• EMBL: AF480544;AF480544
• EMBL: AF480501;AF480501
• HGNC: 31491;MIR103-2
• ENTREZGENE: 406896;MIR103-2

Gene family

MIPF0000024; mir-103

Mature sequence MIMAT0000101

• Accession: MIMAT0000101
• ID: hsa-miR-103
• Sequence: 48 - agcagcauuguacagggcuauga - 70
• Evidence: experimental; cloned [1-4], Northern [2]
• Predicted targets:
  • MICROCOSM:hsa-miR-103
  • TARGETSCAN:hsa-miR-103
  • PICTAR-VERT:hsa-miR-103

Minor miR* sequence MIMAT0009196

• Accession: MIMAT0009196
• ID: hsa-miR-103-2*
• Sequence: 11 - agcuucuuuacagugcugccuug - 33
• Evidence: experimental; 454 [5]
• Predicted targets:
  • MICROCOSM:hsa-miR-103-2*
  • TARGETSCAN:hsa-miR-103-2*

References

1. "miRNPs: a novel class of ribonucleoproteins containing numerous microRNAs" Mourelatos Z, Dostie J, Paushkin S, Sharma A, Charroux B, Abel L, Rappsilber J, Mann M, Dreyfuss G Genes Dev. 16:720-728(2002).
2. "Human embryonic stem cells express a unique set of microRNAs" Suh MR, Lee Y, Kim JY, Kim SK, Moon SH, Lee JY, Cha KY, Chung HM, Yoon HS, Moon SY, Kim VN, Kim KS Dev Biol. 270:488-498(2004).
3. "A mammalian microRNA expression atlas based on small RNA library sequencing" Landgraf P, Rusu M, Sheridan R, Sewer A, Iovino N, Aravin A, Pfeffer S, Rice A, Kamphorst AO, Landthaler M, Lin C, Socci ND, Hermida L, Fulci V, Chiaretti S, Foa R, Schliwka J, Fuchs U, Novosel A, Muller RU, Schermer B, Bissels U, Inman J, Phan Q, Chien M Cell. 129:1401-1414(2007).
4. "Patterns of known and novel small RNAs in human cervical cancer" Lui WO, Pourmand N, Patterson BK, Fire A Cancer Res. 67:6031-6043(2007).
5. "Identification of novel Epstein-Barr virus microRNA genes from nasopharyngeal carcinomas" Zhu JY, Pfuhl T, Motsch N, Barth S, Nicholls J, Grasser F, Meister G J Virol. 83:3333-3341(2009).