Stem-loop sequence hsa-mir-24-2

AccessionMI0000081 (change log)
Symbol HGNC:MIR24-2
DescriptionHomo sapiens miR-24-2 stem-loop
Gene family MIPF0000041; mir-24
Community annotation

This text is a summary paragraph taken from the Wikipedia entry entitled mir-24_microRNA_precursor_family. miRBase and Rfam are facilitating community annotation of microRNA families and entries in Wikipedia. Read more ...

The miR-24 microRNA precursor is a small non-coding RNA molecule that regulates gene expression. microRNAs are transcribed as ~70 nucleotide precursors and subsequently processed by the Dicer enzyme to give a mature ~22 nucleotide product. In this case the mature sequence comes from the 3' arm of the precursor. The mature products are thought to have regulatory roles through complementarity to mRNA. miR-24 is conserved in various species, and is clustered with miR-23 and miR-27, on human chromosome 9 and 19. Recently, miR-24 has been shown to suppress expression of two crucial cell cycle control genes, E2F2 and Myc in hematopoietic differentiation and also to promote keratinocyte differentiation by repressing actin-cytoskeleton regulators PAK4, Tsk5 and ArhGAP19.

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        cc   cg   -cu         --aa      u 
5' cucug  ucc  ugc   acugagcug    acacag u
   |||||  |||  |||   |||||||||    |||||| g
3' gggac  agg  acg   ugacucggu    uguguu g
        -a   --   acu         caca      u 
Get sequence
Deep sequencing
372803 reads, 4.69e+03 reads per million, 77 experiments
Confidence Annotation confidence: high
Feedback: Do you believe this miRNA is real?

mir-24-2 was identified independently by two groups. This sequence was named miR-24 precursor-19 in reference [2].

Genome context
Coordinates (GRCh38; GCA_000001405.15) Overlapping transcripts
chr19: 13836287-13836359 [-]
Clustered miRNAs
< 10kb from hsa-mir-24-2
hsa-mir-23achr19: 13836587-13836659 [-]
hsa-mir-27achr19: 13836440-13836517 [-]
hsa-mir-24-2chr19: 13836287-13836359 [-]
Database links

Mature sequence hsa-miR-24-2-5p

Accession MIMAT0004497
Previous IDshsa-miR-24-2*

13 - 


 - 34

Get sequence
Deep sequencing2868 reads, 71 experiments
Evidence experimental; cloned [6]
Database links
Predicted targets

Mature sequence hsa-miR-24-3p

Accession MIMAT0000080
Previous IDshsa-miR-24

50 - 


 - 71

Get sequence
Deep sequencing740096 reads, 77 experiments
Evidence experimental; cloned [1,4-7], Northern [1], Illumina [8]
Database links
Predicted targets


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PMID:17616659 "Patterns of known and novel small RNAs in human cervical cancer" Lui WO, Pourmand N, Patterson BK, Fire A Cancer Res. 67:6031-6043(2007).