Stem-loop sequence cel-mir-51

Accession

MI0000022 (change log)

Description

Caenorhabditis elegans miR-51 stem-loop

Gene family

MIPF0000268; mir-51

Literature search

7 open access papers mention cel-mir-51
(77 sentences)

Stem-loop

   -------- -   gaaaa u    c    c   g  c  a       -    ggu 
5'         g ucc     g ccgu uacc gua cu cu uccaugu uacu   c
           | |||     | |||| |||| ||| || || ||||||| ||||    
3'         c ggg     c ggca gugg cau ga ga agguaca guga   a
   ucgaagua u   augag -    c    a   g  c  -       a    aaa 

Deep sequencing

267031 reads, 1.78e+03 reads per million, 17 experiments

Confidence

Annotation confidence: high

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Genome context

• Coordinates (WBcel235; GCA_000002985.3): chrIV: 11026013-11026112 [-]
• Overlapping transcripts:

  intergenic

Clustered miRNAs

< 10kb from cel-mir-51

• cel-mir-53: chrIV: 11027593-11027691 [-]
• cel-mir-51: chrIV: 11026013-11026112 [-]

Database links

• RNAcentral:URS00003FDD8B_6239
• Rfam:mir-10
• miRBase Tracker:MI0000022

Mature sequence cel-miR-51-5p

• Accession: MIMAT0000022
• Previous IDs: cel-miR-51
• Sequence: 17 - uacccguagcuccuauccauguu - 39
• Deep sequencing: 253640 reads, 17 experiments
• Evidence: experimental; cloned [1-3], 454 [4], Illumina [5], CLIPseq [6]
• Database links:
  • RNAcentral:URS000041A11D_6239
• Predicted targets:
  • TargetScanWorm:cel-miR-51
  • microrna.org:cel-miR-51-5p

Mature sequence cel-miR-51-3p

• Accession: MIMAT0015099
• Previous IDs: cel-miR-51*
• Sequence: 57 - cauggaagcagguacaggugca - 78
• Deep sequencing: 13354 reads, 17 experiments
• Evidence: experimental; CLIPseq [6]
• Database links:
  • RNAcentral:URS0000313C3C_6239
• Predicted targets:
  • microrna.org:cel-miR-51-3p

References

1. PMID:11679671 "An abundant class of tiny RNAs with probable regulatory roles in Caenorhabditis elegans" Lau NC, Lim LP, Weinstein EG, Bartel DP Science. 294:858-862(2001).
2. PMID:12672692 "The microRNAs of Caenorhabditis elegans" Lim LP, Lau NC, Weinstein EG, Abdelhakim A, Yekta S, Rhoades MW, Burge CB, Bartel DP Genes Dev. 17:991-1008(2003).
3. PMID:12747828 "MicroRNAs and other tiny endogenous RNAs in C. elegans" Ambros V, Lee RC, Lavanway A, Williams PT, Jewell D Curr Biol. 13:807-818(2003).
4. PMID:17174894 "Large-scale sequencing reveals 21U-RNAs and additional microRNAs and endogenous siRNAs in C. elegans" Ruby JG, Jan C, Player C, Axtell MJ, Lee W, Nusbaum C, Ge H, Bartel DP Cell. 127:1193-1207(2006).
5. PMID:19460142 "Dynamic expression of small non-coding RNAs, including novel microRNAs and piRNAs/21U-RNAs, during Caenorhabditis elegans development" Kato M, de Lencastre A, Pincus Z, Slack FJ Genome Biol. 10:R54(2009).
6. PMID:20062054 "Comprehensive discovery of endogenous Argonaute binding sites in Caenorhabditis elegans" Zisoulis DG, Lovci MT, Wilbert ML, Hutt KR, Liang TY, Pasquinelli AE, Yeo GW Nat Struct Mol Biol. 17:173-179(2010).